After years of treatment at a mental institution for the criminally insane, serial killer Norman Bates is finally released. Deciding to move back into his long-dead mother's infamous old house, he soon finds himself tormented by 'her' demands and begins to question his own sanity.
Rita Rizzoli is a narcotics cop with a plethora of disguises. When a drug shipment is hijacked, the thieves don't know that the drug is unusually pure and packs of 'Fatal Beauty' begin turning up next to too many dead bodies. Mike works for the original owner of the drugs and tries to tell himself that since he does not handle the drugs, he is 'clean'. Mike becomes Rita's constant companion.
Charley Brewster, a high school student, accidentally discovers the true and creepy nature of Jerry Dandrige, his dashing and enigmatic new neighbor; but no one seems willing to believe him.
A jet leaves on a red-eye flight from Los Angeles to Boston. But early in the flight, ten passengers awaken to a startling realization: All of the other passengers have vanished.