When Dr. Marcus Sommers realizes that he and his troubled, estranged brother David may be prone a fatal brain disease that runs in their family, he decides to make peace with his sibling, and invites him on a trip to the Rockies. There, the brothers bond over their shared enthusiasm for cycling and decide to enter a grueling bike race through the mountains. However, Marcus' health soon begins to fail, and David must compete without his brother at his side.
Life imitates art when two Manhattanites — pompous teacher Willie and quiet photographer Phil — become friends after a thought-provoking screening of "Jules et Jim," Truffaut's classic film about a decades-long ménage à trois. Soon, the men meet Jeanette, a sexually liberated southern transplant who promptly falls for both of them. Frustrated passions curdle into jealousy as Jeanette entertains love affairs with each in the ensuing years.