During shopping for Christmas, Frank and Molly run into each other. This fleeting short moment will start to change their lives, when they recognize each other months later in the train home and have a good time together. Although both are married and Frank has two little kids, they meet more and more often, their friendship becoming the most precious thing in their lives.
The story of Karen Silkwood, a metallurgy worker at a plutonium processing plant who was purposefully contaminated, psychologically tortured and possibly murdered to prevent her from exposing blatant worker safety violations at the plant.
Substance-addicted Hollywood actress, Suzanne Vale is on the skids. After a spell at a detox centre her film company insists as a condition of continuing to employ her that she live with her mother, herself once a star and now a champion drinker. Such a set-up is bad news for Suzanne who has struggled for years to get out of her mother's shadow, and who still treats her like a child. Despite these and other problems, Suzanne begins to see the funny side of her situation, and also realises that not only do daughters have mothers—mothers do too.
Rachel is a food writer at a New York magazine who meets Washington columnist Mark at a wedding and ends up falling in love with him despite her reservations about marriage. They buy a house, have a daughter, and Rachel thinks they are living happily ever after until she discovers that Mark is having an affair while she is waddling around with a second pregnancy.
When one of his patients is found murdered, psychiatrist Dr. Sam Rice is visited by the investigating officer but refuses to give up any information. He's then visited by the patient's mistress, Brooke Reynolds, whom he quickly falls for despite her being a likely murder suspect. As the police pressure on him intensifies, Rice decides to attempt solving the case on his own and soon discovers that someone is trying to kill him as well.
Madeline is married to Ernest, who was once arch-rival Helen's fiance. After recovering from a mental breakdown, Helen vows to kill Madeline and steal back Ernest. Unfortunately for everyone, the introduction of a magic potion causes things to be a great deal more complicated than a mere murder plot.
A leukemia patient attempts to end a 20-year feud with her sister to get her bone marrow.
While on a family vacation, rafting expert Gail takes on a pair of armed killers while navigating a spectacularly violent river.