Novelist Paul Sheldon crashes his car on a snowy Colorado road. He is found by Annie Wilkes, the "number one fan" of Paul's heroine Misery Chastaine. Annie is also somewhat unstable, and Paul finds himself crippled, drugged and at her mercy.
An uptight New York tax lawyer gets his life turned upside down, all in a single day, when he's asked to escort a feisty and free-spirited female ex-convict whom asks him to help prove her innocence of her crime.
Mark wants to lose his virginity, but his girlfriend wants to wait. Unfortunately for both of them, a 400-year-old vampire Countess needs to turn a virgin into a vampire before Halloween in order to preserve her own youthful appearance, and when she finds Mark, she turns his life upside-down.