The Newton family live in their comfortable home, but there seems to something missing. This "hole" is filled by a small puppy, who walks into their home and their lives. Beethoven, as he is named, grows into a giant of a dog... a St Bernard. Doctor Varnick, the local vet has a secret and horrible sideline, which requires lots of dogs for experiments. Beethoven is on the bad doctor's list.
Wimpy young executive, Michael is about to get pulverised by a jealous boyfriend in a bar when a handsome, mysterious stranger steps in— and then disappears. Later that night, Michael runs into a stranger on a pier, who wheedles his way into Michael's life and turns it upside down.
Tess McGill is an ambitious secretary with a unique approach for climbing the ladder to success. When her classy, but villainous boss breaks a leg skiing, Tess takes over her office, her apartment and even her wardrobe. She creates a deal with a handsome investment banker that will either take her to the top, or finish her off for good.
Stripped of his medical license after performing an operation while high on amphetamines, famed LA surgeon Dr Eugene Sands abandons his former life only to find himself crossing paths with Raymond Blossom, an infamous counterfeiter. Employed as a "gun-shot doctor" when Raymond's associates cannot risk visiting a hospital, Eugene is lured deep into the criminal world and becomes entangled with his boss's girlfriend.
Mulder and Scully, now taken off the FBI's X Files cases, must find a way to fight the shadowy elements of the government to find out the truth about a conspiracy that might mean the alien colonization of Earth.