In the later 1960s, two hippies are forced to leave their friends as they are wanted by the FBI, who sees them as criminals. They hide in the jungle for 20 years, secluded from the outside world. In the later 1980s, the find out that a secret war is about to start in the US, and decide to return to New York to tell someone about it.
Rita Rizzoli is a narcotics cop with a plethora of disguises. When a drug shipment is hijacked, the thieves don't know that the drug is unusually pure and packs of 'Fatal Beauty' begin turning up next to too many dead bodies. Mike works for the original owner of the drugs and tries to tell himself that since he does not handle the drugs, he is 'clean'. Mike becomes Rita's constant companion.
Seth Gecko and his younger brother Richard are on the run after a bloody bank robbery in Texas. They escape across the border into Mexico and will be home-free the next morning, when they pay off the local kingpin. They just have to survive 'from dusk till dawn' at the rendezvous point, which turns out to be a Hell of a strip joint.
Mariachi plunges headfirst into the dark border underworld when he follows a trail of blood to the last of the infamous Mexican drug lords, Bucho, for an action-packed, bullet-riddled showdown. With the help of his best friend and a beautiful bookstore owner, the Mariachi tracks Bucho, takes on his army of desperados, and leaves a trail of blood of his own.