William Thacker is a London bookstore owner whose humdrum existence is thrown into romantic turmoil when famous American actress Anna Scott appears in his shop. A chance encounter over spilled orange juice leads to a kiss that blossoms into a full-blown affair. As the average bloke and glamorous movie star draw closer and closer together, they struggle to reconcile their radically different lifestyles in the name of love.
On a visit to Wisteria Lodge, Scott Eccles gets a strange reception. A mysterious note arrives for his host, Garcia, and the next morning Garcia and his servants have vanished without trace. Eccles consults Holmes, who decides to treat the case as a murder investigation, but it appears that Holmes and Watson are on a wild goose chase.