Two punks from the big city, traveling across the country in a Volkswagen bug, embrace the western ethos when they must take revenge against a group of rednecks for killing their friend in this lighthearted road movie. Along the way, they enlist the help of a young woman who runs a wrecking service.
After breaking up with her girlfriend, a nightclub singer, Jane, answers a personal ad from Robin, a real estate agent with AIDS, seeking a cross-country travel partner. On their journey from New York City to Los Angeles, the two stop by Pittsburgh to pick up Robin's friend Holly, who is trying to escape an abusive relationship. With three distinct personalities, the women must overcome their differences to help one another.
A prototype enhanced human, on the run from Chinese-hired hit men, hooks up with a dread-locked bystander, and the two of them elude their pursuers narrowly each time.
Lloyd and Harry are two men whose stupidity is really indescribable. When Mary, a beautiful woman, loses an important suitcase with money before she leaves for Aspen, the two friends (who have found the suitcase) decide to return it to her. After some "adventures" they finally get to Aspen where, using the lost money they live it up and fight for Mary's heart.
A mom and her 10-year-old son motor around the country as she makes ends meet by turning tricks until her car breaks down. She then temporarily takes up with a hardware store owner until she gets her own place. Then the kid's father shows up to try to take the two over.
Advertising executive Nick Beame learns that his wife is sleeping with his employer. In a state of despair, he encounters a bumbling thief whose attempted carjacking goes awry when Nick takes him on an involuntary joyride. Soon the betrayed businessman and the incompetent crook strike up a partnership and develop a robbery-revenge scheme. But it turns out that some other criminals in the area don't appreciate the competition.
After a young boy is almost runover by a maniac on a highway, a re-encounter and confrontation by the boy's father with the driver sets off conflicts with a carful of maniacs.
Rebelling against his dreary life in a small Arizona town, salesman Nick abandons his girlfriend, Beth, and strikes out onto the highway in search of... something else. Encouraged by her best friend, Carol, Beth reluctantly accepts the romantic attentions of Sid, a local housepainter.
New York City. Melvin Udall, a cranky, bigoted, obsessive-compulsive writer, finds his life turned upside down when neighboring gay artist Simon is hospitalized and his dog is entrusted to Melvin. In addition, Carol, the only waitress who will tolerate him, must leave work to care for her sick son, making it impossible for Melvin to eat breakfast.
While on detention, a group of misfits and slackers have to write a letter to the President explaining what is wrong with the education system. There is only one problem, the President loves it! Hence, the group must travel to Washington to meet the Main Man.
A group of young people leave Harlem for a bus trip down to Miami. The voyage starts off with problems, but it ends up becoming a learning experience, as they end up finding things out about each other they had not previously known.