Lin McAdam rides into town on the trail of Dutch Henry Brown, only to find himself in a shooting competition against him. McAdam wins the prize, a one-in-a-thousand Winchester rifle, but Dutch steals it and leaves town. McAdam follows, intent on settling his old quarrel, while the rifle keeps changing hands and touching a number of lives.
In order to foil a terrorist plot, an FBI agent undergoes facial transplant surgery and assumes the identity of a criminal mastermind, who murdered his only son. The plan turns sour when the criminal wakes up prematurely and seeks revenge.
In a future society in the era of indefinite eugenics, humans are set on a life course depending on their DNA. Young Vincent Freeman is born with a condition that would prevent him from space travel, yet is determined to infiltrate the GATTACA space program.