An FBI informant has kept his new identity secret for 15 years. Now an old flame has recognised him, and the bad guys are back for revenge.
Stripped of his medical license after performing an operation while high on amphetamines, famed LA surgeon Dr Eugene Sands abandons his former life only to find himself crossing paths with Raymond Blossom, an infamous counterfeiter. Employed as a "gun-shot doctor" when Raymond's associates cannot risk visiting a hospital, Eugene is lured deep into the criminal world and becomes entangled with his boss's girlfriend.
After a friend overdoses, Spoon and Stretch decide to kick their drug habits and attempt to enroll in a government detox program. Their efforts are hampered by seemingly endless red tape, as they are shuffled from one office to another while being chased by drug dealers and the police.
The hopes and dreams of four ambitious people are shattered when their drug addictions begin spiraling out of control. A look into addiction and how it overcomes the mind and body.