A blind woman, her husband and another couple sail off to find cash hidden on an island near Cuba.
An American professional gambler named Jack Weil decides to visit Havana, Cuba to gamble. On the boat to Havana, he meets Roberta Duran, the wife of a revolutionary, Arturo. Shortly after their arrival, Arturo is taken away by the secret police, and Roberta is captured and tortured. Jack frees her, but she continues to support the revolution.
In the continuing saga of the Corleone crime family, a young Vito Corleone grows up in Sicily and in 1910s New York. In the 1950s, Michael Corleone attempts to expand the family business into Las Vegas, Hollywood and Cuba.
In 1839, the slave ship Amistad set sail from Cuba to America. During the long trip, Cinque leads the slaves in an unprecedented uprising. They are then held prisoner in Connecticut, and their release becomes the subject of heated debate. Freed slave Theodore Joadson wants Cinque and the others exonerated and recruits property lawyer Roger Baldwin to help his case. Eventually, John Quincy Adams also becomes an ally.