After his brother Robeson disappears without a trace while exploring Africa in search of a legendary 'white tribe', Allan Quatermain decides to follow in his footsteps to learn what became of him. Soon after arriving, he discovers the Lost City of Gold, controlled by the evil lord Agon, and mined by his legions of white slaves.
In 2257, a taxi driver is unintentionally given the task of saving a young girl who is part of the key that will ensure the survival of humanity.