A small, seemingly innocuous plastic reel of film leads surveillance specialist Tom Welles down an increasingly dark and frightening path. With the help of the streetwise Max, he relentlessly follows a bizarre trail of evidence to determine the fate of a complete stranger. As his work turns into obsession, he drifts farther and farther away from his wife, family and simple life as a small-town PI.
Cocky researcher Sebastian Caine is working on a project to make living creatures invisible. Determined to achieve the ultimate breakthrough, Caine pushes his team to move to the next phase — using himself as the subject. The test is a success, but when the process can't be reversed and Caine seems doomed to future without flesh, he starts to turn increasingly dangerous.